We offer our knoweledge and expeirience in GPCR functional assays, cell lines culture and assay development.The purpose of this domain is to establish scientific cooperation between the Department of Neurobiology of the Maj Institute of Pharmacology of the Polish Academy of Sciences that offers its competence in the field of in vitro functional GPCR assays include screening and profiling in drug discovery and pharmacodynamic research. This action is intended to increase access to pharmacodynamic methods for the global drug chemistry environment, focused on the research of new ligands of metabotropic receptors.
The cell lines have been validated in terms of presence of the receptor coding mRNA (RT-PCR), receptor proteins (Western blot) and functional assay (cAMP accumulation, IP1, Ca2 +) in presence of the reference coumponds.
We are members of Department of Neurobiology, highly specialized in a pharmacodynamic and molecular biology:
Department of Neurobiology IF PAS - HEAD: PhD Joanna Wierońska
PhD P. Brański, PhD G. Burnat
3th floor; room: 3.22, 3.23, 3.24 or 3.20
Maj Institute of Pharmacology of the Polish Academy of Sciences
ul. Smętna 12